1) Cat. No.: TRC-H939800; 2) Chemical Name: 2-Hydroxyisoquinoline-1,3(2H,4H)-dione; 3) CAS No.: 6890-08-0; 4) Mol. Formula: C9H7NO3; 5) Mol. Weight: 177.16; 6) Packing Size: 100mg / 1g; 7) Appearence: Brown Solid; 8) Application Notes: 2-Hydroxyisoquinoline-1,3(2H,4H)-dione was recently discovered as a scaffold for the inhibition of HIV-1 integrase and the RNase H function of HIV-1 reverse transcriptase. It was investigated its interaction with Mg2+ and Mn2+ using different spectroscopic techniques and report that 2-hydroxyisoquinoline-1,3(2H,4H)-dione forms a 1:1 complex with Mg2+ but a 1:2 complex with Mn2+. Antiviral agent.; 9) Synonym: 2-Hydroxy-1,3(2H,4H)-isoquinolinedione; ; 10) Solubility: DMSO; 11) Storage condition: Refrigerator; 12) References: Greenwald, J., et al.: Biochemistry, 38, 8892 (1999), Tramontano, E., et al.: Antiviral Res., 65, 117 (2005), Schultz, S., et al.: Virus Res., 134, 86 (2008), Williams, P., et al.: Bioorg. Med. Chem. Lett., 22, 6754 (2010),